Wellness . Symptoms guide
Inflammation Marker Testing (CRP, ESR)
Quick answer
C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are simple, well-established markers of inflammation. They are useful when investigating unexplained fatigue, joint symptoms, post-viral recovery, or for getting a baseline before starting an anti-inflammatory diet or treatment plan.
This patient information is being clinically reviewed by our team. The factual content draws on UK guidance (NHS, NICE, British Association of Dermatologists, and other specialist society guidance where cited).
What this might be
- Post-viral inflammation. Persistent low-grade CRP elevation after COVID or other viral illness.
- Autoimmune disease. Raised inflammation markers warrant further investigation.
- Chronic infection. Hidden infection sources.
- Cardiovascular risk research context. High-sensitivity CRP has been associated with cardiovascular risk in research, although it is not part of the UK QRISK3 calculator used in routine clinical practice.
Common features that suggest this
- Persistent fatigue
- Joint or muscle aches
- Post-viral recovery monitoring
- Baseline before lifestyle change
Recommended tests
Same-day appointments at our Harley Street clinic, results clinician-reviewed.
Need a marker not in these panels? Build a custom panel and a GMC-registered clinician will design one for you.
Markers your clinician will commonly look at
These are the individual blood markers in the recommended panels above. Click any to read what it measures, its UK reference range, and what high or low values mean.
Testing advice
No fasting required. CRP and ESR are included in the Advanced Hair and Hormone Check and can be added to any custom panel.
Common questions
What does a high CRP mean?
Acute inflammation, infection, or sometimes chronic conditions. Modestly raised levels are common after a recent illness.
Related symptoms
Sources and further reading
- NICE CKS: Polymyalgia rheumatica (ESR and CRP interpretation)
- NICE NG188: COVID-19 rapid guideline - managing the long-term effects of COVID-19
This page provides general information only and is not a substitute for medical advice. A GMC-registered clinician will review your results and tailor any recommendations to you personally.