Vitamins and nutrition . Patient guide

Selenium Blood Test

What is Selenium

Selenium is a trace mineral essential for thyroid hormone metabolism, antioxidant defence (glutathione peroxidase), and immune function. UK soil is naturally low in selenium so dietary intake is lower than in many other countries, making selenium status a clinically relevant marker.

This biomarker entry is being clinically reviewed by our team. The factual content draws on UK guidance (NICE, NHS, Royal Colleges and the relevant speciality society where cited).

Reference range

Reported in µmol/L (also seen as µg/L (multiply µmol/L by 79)). Final reports always carry the issuing laboratory's range, which is what your clinician will interpret against.

Group Range Note
Adequate (UK adults) 0.89 to 1.65 µmol/L
Borderline / deficient 0.70 to 0.89  
Deficient under 0.70  
Excess (review supplementation) over 1.90  

What it is

Selenium is incorporated into selenoproteins, including the deiodinase enzymes that convert thyroxine (T4) into the active hormone triiodothyronine (T3), and into glutathione peroxidase, a key antioxidant. UK food sources include Brazil nuts (by far the highest), seafood, organ meats, and eggs.

Why a clinician would order it

Selenium is checked in autoimmune thyroid disease (particularly Hashimoto's, where adequate selenium reduces TPO antibody levels in some studies), in unexplained fatigue or low immunity, in patients with restricted diets, and as part of comprehensive wellness screening. Particularly relevant in patients investigating thyroid hair loss.

If your level is outside the range

Symptoms of low Selenium

  • Fatigue
  • Hair loss
  • Frequent infections
  • Brittle nails
  • Possible worsening of autoimmune thyroid disease

What low can indicate. Inadequate dietary intake (UK diet without Brazil nuts or organ meats often runs marginal), malabsorption, restrictive eating, or increased demand in autoimmune thyroid disease.

Symptoms of high Selenium

  • Garlic-like breath
  • Brittle nails or nail loss
  • Hair loss (paradoxically - high selenium can also cause hair shedding)
  • Skin rash
  • Nausea, fatigue

What high can indicate. Excessive Brazil nut intake (selenium content per nut typically 70 to 90 micrograms but highly variable, and the NHS guidance for supplemental selenium is up to 350 micrograms daily), or over-supplementation.

Testing tips

No fasting required. Hold selenium supplements for at least 48 hours before testing. Note Brazil nut intake when discussing results. Selenium is one of the few nutrients where excess can mimic deficiency in causing hair loss, so supplementation should be guided by a measured baseline.

Where you can get this tested

Selenium is included in the following WMG Health panels. Same-day appointments at our Harley Street clinic, with results clinician-reviewed.

The Hormone Specialist
£299
View panel

Want a specific combination of markers we do not have a panel for? Build a custom panel and our clinicians will design one for you.

Symptoms often investigated with Selenium

Selenium is commonly tested when patients present with the following symptoms. If any of these resonate with you, the linked guides explain what to look for and which test pathway is appropriate.

Thinning at the Crown: Hormonal and Nutritional Causes Crown thinning is the classic site of androgenetic alopecia in men and FPHL in women. Blood tests pin down ... Read symptom guide → Female Hair Loss: What to Test Female hair loss is rarely one thing. Iron, thyroid, oestrogen, androgens and ferritin all overlap. Test th... Read symptom guide → Low Testosterone in Men: When to Test Persistent fatigue, low libido, mood changes and reduced muscle strength can signal low testosterone. Test ... Read symptom guide → Low Libido in Men: What Blood Tests Show Low libido is rarely just psychological. Testosterone, thyroid, vitamin D, SHBG and pituitary hormones all ... Read symptom guide → Erectile Changes: Blood Work That Matters Erectile changes can be vascular, hormonal or medication-related. A blood panel rules out the metabolic and... Read symptom guide → Andropause (Male Menopause): Symptoms and Testing Andropause covers age-related testosterone decline plus the symptoms it drives. A morning testosterone, fre... Read symptom guide →

Related markers

Thyroid-Stimulating Hormone (TSH) Thyroid Free Thyroxine (Free T4) Thyroid Free Triiodothyronine (Free T3) Thyroid Zinc Vitamins and nutrition

Sources

UK guidance our clinicians use when interpreting this marker.

This page is general patient information, not personal medical advice. A GMC-registered clinician will review your results and tailor any interpretation to you. See our Editorial Policy for how we write and review content.

Common questions about Selenium

What is a normal Selenium range?

Adequate (UK adults): 0.89 to 1.65 (µmol/L). Borderline / deficient: 0.70 to 0.89. Deficient: under 0.70. Excess (review supplementation): over 1.90. Always interpret your own results against the laboratory range printed on your report, since assay-specific reference ranges vary.

What does a low Selenium result mean?

Inadequate dietary intake (UK diet without Brazil nuts or organ meats often runs marginal), malabsorption, restrictive eating, or increased demand in autoimmune thyroid disease.

What does a high Selenium result mean?

Excessive Brazil nut intake (selenium content per nut typically 70 to 90 micrograms but highly variable, and the NHS guidance for supplemental selenium is up to 350 micrograms daily), or over-supplementation.

Do I need to fast or prepare for the Selenium blood test?

No fasting required. Hold selenium supplements for at least 48 hours before testing. Note Brazil nut intake when discussing results. Selenium is one of the few nutrients where excess can mimic deficiency in causing hair loss, so supplementation should be guided by a measured baseline.

Can I order a Selenium blood test privately in London?

Yes. WMG Health offers Selenium as part of bespoke panels and several pre-built panels at our 134 Harley Street clinic. Results are clinician-reviewed by a GMC-registered doctor within 4 hours for the most common assays. All panels are custom-built around your specific question; bookings via /contact/ or 020 3239 3378.